The material selection platform
Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients


CAS Number 111-02-4
Chem/IUPAC Name: 2,6,10,15,19,23-Hexamethyltetracosa-2,6,10,14,18,22-hexaene
EINECS/ELINCS No: 203-826-1
COSING REF No: 78861
Squalene is a natural compound found in human sebum and various plant sources. In cosmetics, it is a popular emollient and moisturizer due to its excellent skin compatibility. Squalene helps restore the skin's lipid barrier, preventing moisture loss and enhancing skin softness. Its lightweight texture makes it easily absorbed without leaving a greasy residue. Furthermore, Squalene possesses antioxidant properties, protecting the skin from environmental stressors like UV radiation and pollution. Sometimes, Squalene proves to be even better than hyaluronic acid due to its ability to mimic skin’s natural oils. However, they are largely complementary to each other due to their similar benefits. The chemical formula of Squalene is C30H50.

What is SQUALENE used for?

Squalene boasts versatile uses in skincare and cosmetics due to its excellent moisturizing and emollient properties. As a lightweight and non-greasy oil, it effectively hydrates the skin without clogging pores, making it suitable for all skin types. Squalene helps to replenish the skin's lipid barrier, improving elasticity and suppleness while reducing transepidermal water loss. Its antioxidant properties also protect the skin from environmental stressors, such as UV radiation and pollution, promoting a healthy complexion. Squalene is commonly found in moisturizers, serums, facial oils, and other skincare products, supporting overall skin health and radiance.


Squalene is primarily sourced from natural ingredients such as shark liver oil, olives, and sugarcane. It is extracted through various methods including centrifugation and solvent extraction. Once extracted, Squalene undergoes a purification process to remove impurities and ensure its quality.

What does SQUALENE do in a formulation?

  • Antioxidant
  • Emollient
  • Moisturising
  • Refatting
  • Skin conditioning
  • Smoothing
  • Uv filter

Safety profile

Squalene itself is generally considered safe for topical use in skincare products. However, contamination or impurities in poorly sourced or processed Squalene can pose risks. Some concerns revolve around the sourcing of Squalene from shark liver oil, which raises ethical and environmental issues. Moreover, using excessive amounts of this ingredient or using it on compromised skin barriers may lead to clogged pores or acne breakouts, especially in sensitive individuals.

Technical profile

Property Values
Boiling Point 421.3°C
Melting Point -4.8°C
Solubility Insoluble in water

Commercial Selection : Grades containing solely SQUALENE

Back to Top