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Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients


CAS Number 55406-53-6
Chem/IUPAC Name: 3-Iodo-2-propynyl butylcarbamate
EINECS/ELINCS No: 259-627-5
COSING REF No: 34582
Iodopropynyl Butylcarbamate, also known as IPBC or IPBC preservative, is an antimicrobial ingredient commonly used in cosmetics. It appears as a white, crystalline powder. Iodopropynyl Butylcarbamate is not a paraben; it belongs to a different chemical class called carbamates. Its chemical formula is C9H12IN3O2, and it is soluble in both water and oil-based systems. Iodopropynyl Butylcarbamate is added to cosmetic formulations to prevent microbial growth, thus extending the shelf life of products. It is effective against a broad spectrum of microorganisms. However, it is important to note that this ingredient usage should comply with regulatory guidelines to ensure safe levels of exposure in cosmetic applications.


Iodopropynyl Butylcarbamate is widely used in the cosmetics industry for its antimicrobial properties and preservative capabilities. It is incorporated into various cosmetic formulations to prevent the growth of bacteria, yeast, and mold, thereby extending the shelf life of the products. Iodopropynyl Butylcarbamate is particularly useful in water-based formulations such as lotions, creams, and liquid cosmetics, where microbial contamination can be a concern. By inhibiting the growth of microorganisms, Iodopropynyl Butylcarbamate helps maintain the safety and integrity of cosmetic products, ensuring that they remain free from spoilage and potential health risks, while maintaining their efficacy over time.


Iodopropynyl Butylcarbamate is typically synthesized through a reaction between iodine, butylamine, and carbamic acid. The reaction forms the Iodopropynyl Butylcarbamate compound, which is then further processed and purified to obtain the final product. This synthesis method ensures the production of this ingredient with the desired antimicrobial properties for cosmetic applications.

What does IODOPROPYNYL BUTYLCARBAMATE do in a formulation?

  • Antimicrobial
  • Preservative

Safety profile

Iodopropynyl Butylcarbamate is not entirely safe for use and can cause skin irritation or allergic reactions in some individuals. This necessitates patch testing prior to full usage, especially in the case of sensitive skin. Additionally, Iodopropynyl Butylcarbamate is non-comedogenic and does not cause acne. It is also vegan-friendly since it is not derived from animal sources.


Technical profile

Property Values
Boiling Point 321.8±25.0°C
Melting Point 64-68°C
Solubility Soluble in water
Viscosity Low
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