METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL

CAS Number	103597-45-1
Chem/IUPAC Name:	2,2’-Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol)
EINECS/ELINCS No:	403-800-1 / 921-481-1
COSING REF No:	38987

A broad spectrum UV absorber, Bisoctrizole, also known as methylene bis-benzotriazolyl tetramethylbutylphenol, is a phenolic benzotriazole that absorbs UVB and UVA rays and stabilizes other UV absorbers. It's a "hybrid" sunscreen, which means it transcends the line between chemical sunscreens (those that absorb the rays, which most sunscreens do) and physical sunscreens (the ones that at least partially reflect the sun) and has been described as an organic UV filter produced in microfine organic particles (<200 nm).

Who supplies METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL ?

BASF

DSM

What is METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL used for?

Methylene-bis benzotriazolyl tetramethylbutylphenol works as a sunscreen in cosmetics and personal care products. Since it is one of the few commercially available filters that is photostable, it has an advantage over the vast majority of commercially available filters in terms of photostability. It is a synthetic broad-spectrum UV filter that aids in protecting skin from UVA and UVB rays, with peak protection occurring at 305 nm for UVB and 360 nm for UVA. In this sense, it can also be regarded as an anti-aging component because it delays the accelerated ageing effects brought on by sun exposure.

It provides a combination of chemical and physical sunscreen sun protection. Microfine pigments found in the molecule help reflect and scatter UV light before it can cause damage to skin, and an organic UV light absorber transforms UV light into harmless heat energy that dissipates from the surface of the skin. Its inability to dissolve in either oil or water is another special characteristic. Research has found that it can aid in enhancing the stability of other sunscreen ingredients.

This ingredient's molecular size keeps it on the skin's surface, making it less likely to cause a sensitized reaction in people whose skin is prone to reacting negatively to synthetic UV filters. The drawback of its hybrid nature is that Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, like the inorganic sunscreens zinc and titanium dioxide, also leaves a white cast on the skin that can be bothersome on darker skin tones.

Origin

Methylene-bis benzotriazolyl tetramethylbutylphenol is produced as small particles (<200 nm), like microfine zinc oxide and titanium dioxide. And it is organic like most sunscreen actives. It is added to the water phase of a sunscreen as a 50% suspension, while mineral micropigments are usually added to the oil phase.

What does METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL do in a formulation?

Uv filter

Safety profile

Methylene Bis-Benzotriazolyl tetramethylbutylphenol is a UV filter that is authorized in Europe. As a result, sunscreen products intended to shield the skin from the sun may include the ingredient. The FDA has not yet reviewed the safety and effectiveness of Methylene Bis-Benzotriazolyl tetramethylbutylphenol for sunscreen use, so it cannot be used in sunscreen drug products. Methylene Bis-Benzotriazolyl tetramethylbutylphenol can be used as a UV light absorber in cosmetics in the US.

The European SCCNFP concluded that there was no evidence of allergenicity, phototoxicity or irritation of 2,2″ Methylene-bis-(6-(2H-benzotriazol-2-yl)-4-(1,1,3,3-tetramethylbutyl)phenol), or Methylene Bis-Benzotriazolyl Tetramethylbutylphenol. This ingredient was not genotoxic and did not cause reproductive effects. The dermal absorption of this ingredient was very low.

METHYLENE BIS-BENZOTRIAZOLYL TETRAMETHYLBUTYLPHENOL Alternatives

ZINC OXIDE, TITANIUM DIOXIDE

Technical profile

Property	Values
Boiling Point	~100°C
Melting Point (solid)	195.7°C
pH	10.5-12.0 (25°C)
Solubility	Dispersible in water (temperature unspecified) Soluble in polar cosmetic oils (25°C)