TAGS: Skin Care Sustainability / Natural Cosmetics
Sytheon shares that Synastol® TC is now available as a nutritional supplement. It is claimed to be the first standardized Terminalia chebula Fruit Extract for this use in the industry.
Terminalia chebula is an edible superfruit that’s known for its use in Ayurvedic as a dietary supplement. It treats a wide range of health conditions, including diabetes and arthritis. In skin care, Synastol® TC is a natural and well-defined extract of Terminalia chebula.
When used in topical applications, Synastol® TC is clinically proven to improve the appearance of wrinkles, repair skin barrier dysfunction, and reduce the negative effects of pollution and blue light-induced skin damage.
Gut Health - Overall Well-being, Including Skin Health
Sytheon is an innovative, research-backed company. It is always looking for new ways to use proven ingredients to improve personal care. Sytheon saw the opportunity to take the beneficial, holistic characteristics of TC to the next level by developing an ultra-concentrated and standardized bioactive powder form that can be used as an oral supplement. Synastol® TC delivered in a hard gelatin capsule promises exciting benefits for customers.
Gut health plays an important role in overall well-being, including skin health. When used as an oral supplement, Synastol® TC is linked to improving gut health by elevating microbiome diversity.
In a double-blind, placebo-controlled, 8-week study, subjects took 250 mg capsules of Synastol® TC twice a day. The goal was to see how oral TC affects the gut microbiome and relevant biochemistry. The results were submitted for publication. The results were statistically significant:
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Greater alpha diversity and increased amounts of favorable gut bacteria and phages (p<0.05)
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Akkermansia muciniphila is increasing. It is expected to become a new probiotic, along with Lactobacillus and Bifidobacterium
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Increase in Short Chain Fatty Acid (SCFA, epigenetic regulators) production
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Increase in serum bile acids (effectors of gut microbiome) synthesis
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Increase in production of Acetic Acid (p=0.045)
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Increase in production of Propionic Acid (p=0.001)
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Increasing trend of Butyric Acid (p=0.12)
Beauty from Inside Out
When used as an oral supplement, Synastol® TC successfully targets sebum excretion rate (linked to acne), facial erythema (redness), and wrinkles. In a double-blind, placebo-controlled, 8-week study, subjects took 250 mg capsules of Synastol® TC twice a day. The results showed:
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33% decrease in sebum excretion rate after 8 weeks of Synastol® TC, compared to a 29% increase with placebo
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Statistically significant decrease in cheek erythema after 8 weeks of Synastol® TC treatment, compared to an increase with placebo
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Statistically significant decrease in wrinkles after 8 weeks of Synastol® TC treatment, compared to an increase with placebo
Overall, their findings suggest that oral supplementation with standardized TC extract with highly enriched hydrolyzable tannins has beneficial properties for the skin, which may be due to improved gut health.
Source: Sytheon
