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Shiseido Reveals Impact of Digital Fatigue on Skin Barrier & Moisturizing Functions

Published on 2021-04-06. Edited By : SpecialChem

TAGS:  Skin Care    

Shiseido_Digital_FatigueShiseido Company, Limited (“Shiseido”) has revealed that digital fatigue not only increases physical and mental fatigue but also changes skin conditions, such as deterioration of skin barrier function, irregularity in corneocytes, and increased oxidative damage factor.

It was also found that Shikuwasa extract enhances the expression of caspase-14, an important enzyme for skin barrier and moisturizing functions.

Conducted Digital Fatigue Task


Shiseido has been conducting research on young skin and stress for more than 30 years, and studying the impacts of various stresses on the skin. This time, the researchers focused on the lifestyles among today’s youth of so-called digital natives, such as Gen Z, and successfully evaluated the impacts of digital fatigue on the skin by applying a unique test system.

In this study, the researchers reproduced a state of digital fatigue through dual tasks that required subjects to simultaneously process a high amount of audiovisual information, and observed the changes in skin condition. The team asked the subjects to perform a digital fatigue task for a certain period of time and repeat it over several days.

Results- Causes Rough Skin


The results showed that after repetitive digital fatigue tasks, not only physical and mental fatigue increased, porphyrin, one of oxidative damage factors, also increased. In addition, the proportion of irregular corneocytes increased and the skin barrier function also deteriorated. In other words, after digital fatigue, the skin barrier function may deteriorate and possibly result in causing rough skin.

In order to address the changes in skin condition caused by digital fatigue, the researchers searched for active ingredients that enhance the expression of caspase-14, an enzyme that is essential for skin barrier and moisturizing functions. Caspase-14 plays important roles in maturation of corneocytes, which are responsible for the barrier function and water-holding capacity, as well as assisting in the production of Natural Moisturizing Factor (NMF), which is deeply involved in water-holding capacity in corneocytes.

The team found that Shikuwasa extract has the effect of enhancing the expression of caspase-14, which could suggest that Shikuwasa extract can protect skin from changes in skin condition caused by digital fatigue, and lead to healthy and beautiful skin.

Going forward, Shiseido will continue to promote research closely aligned with consumers’ lifestyles and aim to help them achieve healthy and beautiful skin in their own way.


Source: Shiseido
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