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Shiseido Finds Oxidative Stress Leads to Skin Aging and Wrinkle Formation

Published on 2019-11-22. Edited By : SpecialChem

TAGS:  Skin Care      Sun Care   

Shiseido-skin-sunShiseido has succeeded in evaluating on a “whole face” scale the oxidative stress which accumulates in the skin due to damage such as from UV, by applying biophoton (UPE) measurement technology through an ultra-sensitive cooled CCD (Charge Coupled Device) camera in joint research with Tohoku Institute of Technology.

Evaluated the Oxidative Stress of the Face


The team has revealed for the first time that there are regional differences in the oxidative stress of the face. Furthermore, the team also found that, by using this technology, the oxidative stress level increases with age and is closely correlated with wrinkle formation.

Shiseido will further conduct research and development based on this finding, with the aim of utilization in various fields, such as the development of appropriate skin care and sun care products according to the oxidative stress of each skin region and the recommendation of more effective methods of use.

Conclusions from the Research


Biophoton (UPE) Generated from the Skin


The skin generates extremely faint light called biophoton (UPE), which is invisible to the human eye, and this faint light increases with oxidative stress. In 2018, by using an ultrasensitive cooled CCD camera, Shiseido non-invasively captured an image of biophoton and precisely visualized the oxidative stress of the human skin.

Through this technology, the team has succeeded in providing visual proof that sunscreen defends against UV and protects the skin from oxidative stress, and that green tea leaf extract contained in cosmetics has the effect of suppressing oxidative stress accumulated in the skin due to damage such as from UV.

Evaluated Oxidative Stress of the Whole Face


The team evaluated the oxidative stress of the whole face and found that skin regions between the eyebrows and around the nose are most vulnerable to oxidation compared to others, which is possibly because these facial regions are more likely to be exposed to UV and also contain a lot of sebum.

This suggests the importance of appropriate care according to skin region, such as frequent application of sunscreen and thorough skin care.

Oxidative Stress in Skin Increases with Aging


Using this measurement technology, the team evaluated the oxidative stress of the skin around the eyes of women in each age group, and found that the oxidative stress level of the skin increased in accordance with age and that the higher the level, the greater the score of wrinkles formed.

Oxidative stress in the skin due to UV is considered one of the causes of photoaging. Facial skin is exposed to UV during the day throughout the year, so it is especially important to apply skin care daily. Based on the research results accumulated so far, Shiseido will pursue development of skin care and sun care products that protect the skin from oxidative stress.

These research results were presented in the Poster Presentation category at the IFSCC Conference 2019 held in Milan, Italy from 30th September to 2nd October 2019.


Source: Shiseido
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