TAGS: Skin Care
Amorepacific has performed extensive research and revealed the causal relationship between stress and changes in skin condition, and published the result of a joint study on the effective substance that can improve the deterioration of the skin barrier function due to stress.
Effect of Stress on Skin
A joint research team of Amorepacific and Yonsei University Wonju College of Medicine's Department of Dermatology conducted a long-term study to reveal the effect of stress on the skin. As a result, the mechanism of the adverse effects of stress on the skin was discovered.
An excessive release of stress hormone called 'cortisol' from the adrenal cortex was noted as a major cause of 'skin barrier dysfunction', which undermines skin's protective function against external harmful factors. In addition, when under stress, the skin increases the enzyme (11β-HSD1) that converts the cortisone hormone into the active cortisol hormone, which in turn further increases the level of cortisol in skin thereby damaging the skin including skin barrier.
Hydroxydaidzein Restores Skin Barrier Function
In order to solve the adverse effect of such stress stimulus on the skin, Amorepacific R&D Center has focused on the effectiveness of hydroxydaidzein (7,3',4'-trihydroxyisoflavone), which is released infinitesimally when beans, Amorepacific’s heritage material, are fermented under a specific condition.
Through 10 years of research, the team published that hydroxydaidzein controls the cortisol-receptor response to restore the skin barrier function to a normal level even in stressful situations and maintain a healthy skin condition by inducing pH normalization.
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After a long-term study to find a biomaterial that can restrain skin damage caused by stress, we were able to successfully secure and mass-produce high-purity hydroxydaidzein. Based on the dermatological achievements and effective solutions obtained from the research, Amorepacific will continue to provide innovative solutions for the health and beauty of our customers,” said Park Young-ho, the Head of Amorepacific’s Basic Research & Innovation Division.
Source: Amorepacific