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Active Ingredients for Skin Lightening / Hyperpigmentation Market – Part 4

SpecialChem / Vispi Kanga – Dec 23, 2008

Since the early seventies, research centers around the world have studied the effects of UV light on the skin and the concept of the alteration of the size of melanosomes as a means to affect skin lightening. In the later years, research in this area. In the previous articles we talked about hydroquinone, Arbutins, kojic acid, Alpha hydroxyl acids, monobenzone and melasma. One of the three basic types of skin lightening ingredients is natural ingredients that work by limiting the transfer of pigment into the skin cells. Typical examples of these types of ingredients are Niacinamide and Soy to affect melanosome transfer and thus pigmentation. Niacinamide (nicotinamide) is an effective skin lightener, especially for skin conditions where hyperpigmention may occur on the face or other visible parts of the body. Niacinamide was found to reduce hyper pigmentation in a pigmented reconstructed epidermal (PREP) model by inhibiting 35-68% of melanosome transfer from melanocytes to keratinocytes.

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