Givaudan Asiaticoside

Asiaticoside. Used in restructuring creams, anti hair loss lotions and nail care products. Possesses anti-wrinkle properties. Asiaticoside can be easily solubilized in many hydrophilic solvents(propylenglycol, glycerin, ethoxydiglycol,...) commonly used in the manufacturing of topical formulations (gel, emulsion, ...). If an emulsion has to be prepared, Asiaticoside is incorporated in the hydrophilic portion, before emulsyfication with the lipophilic phase. Collagen, the predominant matrix skin protein, is known to impart tensile strength to skin. In particular, among different collagen types (about 28 forms) the I form is the most abundant of the human body: it is present in scar tissue, the final product when tissue heals by repair, it is also found in tendons, the endomysium of myofibrils and the organic part of the bone. The type III is collagen of granulation tissue, and is produced quickly by young fibroblasts before the tougher type I collagen is synthesized, it is also found in artery walls, intestines and the uterus.