The material selection platform
Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients
by SpecialChem
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Technical Datasheet | Supplied by Clariant
Silybum Marianum Extract (and) Glycerin (and) Aqua. CELYSCENCE™ by Clariant is a senescence preventer for healthy aging. It is an extract of the seedless milk thistle flower (Sylibum marianum) that prevents the accumulation of senescent cells (zombie cells) in the skin.
  • It uses triple mode of action and restores skin healthiness.
  • It induces apoptosis in senescent cells without affecting non-senescent cells.
  • It inhibits the secretion of SASPs by senescent cells, such as interleukins (IL-6 and IL-8) & collagenase (MMP-1), preventing senescence contamination.
  • It possesses the ability to inhibit important senescent cells markers, thus turning a senescent cell into a cell with a young profile.
  • It restores the crucial ability of dermal fibroblasts to produce collagen, ensuring aged tissue repair and remodeling efficacy.
  • CELYSCENCE™ is recommended for formulating creams & lotions, anti-aging creams, neck firming cream and décolleté complexion boosters.
  • Anti-aging Agents
  • Repairing
  • Brightness
  • Bio-based
CAS Number
84604-20-6, 56-81-5, 7732-18-5
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