OK
The material selection platform
Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients
Product News

BASF’s New Ingredient Promotes Healthy Scalp and Microbial Diversity

Published on 2020-04-17. Author : SpecialChem

TAGS:  Hair Care    

BASF_Healthy_ScalpBASF has launched Scalposine™, a true scalp detox that can restore beauty and health. It reduces sebum production and encourages beneficial strains of bacteria.

Scalposine™ Soothes and Purifies Scalp


An unhealthy scalp is often oily, covered with dandruff and can become sensitive. In response, BASF’s new active ingredient is proven to soothe and purify the scalp by decreasing the production of sebum and replenishing scalp microbiota.

With Scalposine (INCI: Glycerin (and) Water (and) Sarcosine), BASF has developed a holistic approach based on Sarcosine, an amino acid derivative found naturally in the human body. It is a precursor of glycine, an amino acid essential for building major skin macromolecules, such as elastin and collagen.

Resetting Microbiome for Healthy Scalp


Virtually unexplored until now, the scalp supports several types of micro-organisms living in harmony with our scalp cells. In a metagenomic study, BASF explored the disruptive influence of sebum on this fragile microbiotic balance. The analysis confirmed that the diversity of the microbiota is lower on an oily scalp than on a normal scalp.

Scalposine when used at 1 percent significantly increased the diversity of the scalp’s microbiota after one month of application – with the number of taxa increasing by 36 percent as compared to the placebo. The active ingredient exhibited a prebiotic effect and boosted recolonization with six strains of bacteria previously identified by BASF researchers as being beneficial for a healthy scalp overall.

Reduces Sebum Production in Hair Follicles


Excessive sebum production in hair follicles not only fosters the reduction of beneficial bacteria strains but irritates the scalp, causes skin flaking and hair to appear greasy. In vitro trials showed that Scalposine at a dose of 0.7 percent effectively reduces the gene expression of 5α-reductase 1, the enzyme initiating the process of sebum production, by as much as 77 percent.

A one-month placebo-controlled clinical study confirmed the active ingredient’s ability to lower the level of scalp sebum. 82 percent of study participants reported an immediate soothing effect on the scalp, while some even saw flakiness decrease after 28 days of application.


Source: BASF
Multifunctional vitamin ingredient
Back to Top