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BASF Launches Biotic Ingredients Based on Bacterium for Skin Care

Published on 2022-06-29. Edited By : SpecialChem

TAGS:  Skin Care    

BASF Launches Biotic Ingredients Based on Bacterium for Skin CareBASF's Care Creations® introduces two new biotic ingredients Probiolift™ and Postbiolift™, that may help maintain more youthful, fresh skin.

In contrast to other biotics on the cosmetics market, the basis of these newly developed active ingredients is, for the first time, a bacterium that is part of the natural microflora of the skin: Lactobacillus crispatus (L. crispatus), a gram-positive, anaerobic rod bacterium whose colonization of the skin has been shown to decrease with age.

Changes in Facial Skin Microbiome with Age

Complementing existing research indicating that the diversity of the skin microbiome changes with age, BASF has conducted a new study on the different compositions of the microflora on the face of young and older people. The research team found that lactic acid bacteria, including lactobacilli, decreased significantly in mature skin.

In particular, the species L. crispatus decreased in the area under the eyes and was no longer detectable in the folds of the older subjects. This finding led the team to believe that L. crispatus, derived from populations on human skin, maybe the key to more youthful-looking skin.

BASF has developed two cosmetic ingredients in one and the same biofermentation process:

  • Probiolift™, a probiotic containing the dormant cultures of live L. crispatus bacteria
  • Postbiolift™, the fermentation supernatant containing the metabolites formed by L. crispatus

Consumers are increasingly aware of the health-promoting properties of biotic ingredients, whether they are pre-, pro-, or post-biotic. This trend has its roots in the food industry," says Cécile Kalem, BASF launch manager for cosmetic active ingredients in Europe.

"What is already common practice in this area has posed one of the biggest challenges for the personal care industry until now: live skin bacteria in cosmetic formulations and keep them active. With Probiolift™, we've managed to do that - a real breakthrough for our R&D teams."

Probiolift™ for Denser Skin with Less Pronounced Wrinkles

Probiolift™ consists of live, dormant L. crispatus bacteria that become active again when they come into contact with water on the skin. The active ingredient opens the door to a new generation of biotic cosmetics for relaxed aging: it contributes to thicker skin and at the same time helps to reduce the development of forehead wrinkles.

29 women between the ages of 45 and 65 who had fine lines or wrinkles on their foreheads took part in the clinical study. The effectiveness of a base cream containing 0.05% Probiolift™ was evaluated in comparison to a placebo base cream. Probiolift™ ensured that the subjects' skin was denser after two months.

Although forehead wrinkles are more difficult to smooth than crow's feet, the new probiotic also brought a visible improvement in this area: the appearance of wrinkles was reduced by 5% compared to the placebo. The clinical results are supported by the biological properties of L. crispatus demonstrated in in vitro tests.

Postbiolift™ for Elastic, Smoother and Even Skin

Postbiolift™ is a new and unique postbiotic agent containing beneficial metabolites produced by L. crispatus. It improves the skin's mechanical properties, smoothes wrinkles around the eyes, and evens out the complexion.

The effectiveness of Postbiolift™ was demonstrated in a placebo-controlled clinical study with 30 female volunteers between the ages of 40 and 50 with crow's feet, wrinkles, and pigment spots on their faces. After 28 and 56 days of treatment with a cream containing 1% of the ingredient, the elasticity parameters were evaluated. The results were significant with an improvement of up to 10% compared to a placebo.

Additionally, at the end of the 56-day study, Postbiolift™ had reduced the appearance of crow's feet and pigmented age spots by almost 7% compared to placebo. The putative mechanisms underlying the observed clinical outcomes have been supported by extensive in vitro studies.

The two new ingredients enable cosmetics manufacturers to meet the increasing demand for clinically proven biotic products that promote youthful skin.

Explore Skin Care Range from BASF

Source: BASF

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