TAGS: Skin Care
Shiseido has revealed that capillaries are involved in skin elasticity by visualizing the 3-dimensional (3D) structure of skin. The company also discovered that yeast extract keeps capillaries healthy and helps the production of collagen, important for maintaining skin elasticity. Based on these findings, skin care products will be developed for elastic skin to prevent skin problems, such as wrinkles and sagging.
Role of Capillaries in Skin Elasticity
Shiseido has conducted research on the relationship between skin elasticity and the state of capillaries using 3D visualization technology and found that capillaries are thick and dense in areas with high elasticity. Through further research, observed that collagen is produced around capillaries. This suggests the possibility of capillaries playing a role in maintaining skin elasticity.
Expression Levels of integrin-α5 in Capillaries
Shiseido’s research revealed that the expression levels of integrin-α5 in capillaries decrease with age along with skin elasticity, thereby suggesting to maintain the expression of integrin-α5 in capillaries.
The company searched for ingredients that increase integrin-α5 expression and confirmed that yeast extract extracted from Saccharomyces yeast is effective. As the result, the team found the possibility that yeast extract increases the expression levels of integrin-α5 which decrease with age, facilitates the production of collagen, and helps create an elastic skin.
Shiseido has conducted research on the relationship between capillaries and skin and reported various findings, including the fact that capillaries which are damaged or decrease due to aging and UV rays are one of the fundamental causes of skin aging.
The research results were presented at IFSCC Conference 2019 in Milan (September 30 to October 2, 2019). It is also scheduled to be presented at the North American Vascular Biology Organization (October 27 to 31, 2019).
Source: Shiseido