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Cosmetics Ingredients
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Cosmetics Ingredients

BISABOLOL

CAS Number 515-69-5 / 23089-26-1 / 23178-88-3 / 25428-43-7
Chem/IUPAC Name: (2R)-6-methyl-2-[(1R)-4-methylcyclohex-3-en-1-yl]hept-5-en-2-ol
EINECS/ELINCS No: 208-205-9 / 245-423-3 / 246-973-7
COSING REF No: 74499
BISABOLOL
Bisabolol, more formally αlpha-bisabolol or also known as levomenol, is a natural monocyclic sesquiterpene alcohol. It is a colorless to light yellow, oily liquid, that is the primary constituent of the essential oil from German chamomile (Matricaria recutita) and Myoporum crassifolium. It is used in cosmetic formulations as a skin conditioning agent. It has a weak sweet floral aroma and is used in various fragrances.

Who supplies BISABOLOL ?

Symrise
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BioOrganic Concepts
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Clariant
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Kyowa Chemical Industry
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MakingCosmetics
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Alfa Chemistry
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What is BISABOLOL used for?

Bisabolol is a safe ingredient used in a wide array of formulations. It is safely used up to 1% concentration in leave-on formulations.
  • Skin care: It has skin healing properties including reducing wrinkles and skin roughness, and repairing sun-damaged skin, and more recently it has been compounded with tretinoin as a topical treatment for acne. Because of its anti-oxidant qualities, bisabolol can help keep skin firm and youthful-looking by visibly reducing the signs of aging. Due to its anti-inflammatory qualities, it frequently plays a bioactive skin-calming role and is found in many products made for sensitive skin. In addition to its calming effects, research suggests bisabolol may have some ability to lighten discoloration. It provides moisturization and relieves dry and itchy, flaky skin.
  • Hair care: Because of its high panthenol concentration, it can effectively stimulate and promote the skin's healing process and encourage healthy hair growth

Origin

German chamomile (Matricaria chamomilla or Matricaria recutita) plants or the Brazilian candeia tree (Vanillosmopsis erythropappa) bark are the two sources used to extract bisabolol. Similar steps are taken in the extraction process as in the distillation of essential oils. Following the extraction of the raw oil, it is refined to separate the desired bisabolol from the other ingredients. It can also be created synthetically using molecular engineering. The procedure entails using human enzymes and organisms like yeast or bacteria to produce the nature-identical molecule, typically through fermentation. Because no trees need to be cut down, this has exciting implications for sustainability. Synthetic bisabolol can also be produced using chemicals. However, since petroleum is a common source of carbon, the resulting bisabolol is of lower purity levels.

What does BISABOLOL do in a formulation?

  • Masking
  • Skin conditioning
  • Soothing

Safety profile

The Food and Drug Administration (FDA) includes German chamomile as Generally Recognized as Safe (GRAS). The flowers of this plant are on the list of GRAS essential oils, oleoresins, and natural extractives. The safety of Bisabolol has been assessed by the Cosmetic Ingredient Review (CIR) Expert Panel. The CIR Expert Panel evaluated scientific data and concluded that Bisabolol was safe as used in cosmetics and personal care products.

BISABOLOL Alternatives

ALLANTOIN, PANTHENOL, CENTELLA ASIATICA EXTRACT

Technical profile

Property Values
Boiling Point 314-315°C
Solubility Insoluble in water
Slightly soluble in ethanol
67

FORMULATIONS with BISABOLOL

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