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The material selection platform
Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients

BIOTIN

CAS Number 58-85-5
Chem/IUPAC Name: 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoic acid
EINECS/ELINCS No: 200-399-3
COSING REF No: 32188
BIOTIN
Biotin is a type of Vitamin B, Vitamin B7 available as a white, crystalline powder. It is present in many foods, but it can also be produced by bacteria in the body. The benefits of biotin supplements for healthy hair, skin, and nails as well as for treating hair loss are frequently idealized. Additionally, it is a common ingredient in shampoos and hair sprays.

What is BIOTIN used for?

Biotin is primarily used for its smoothing and moisturizing qualities. It is thought to enhance the texture of creams and give hair more body, shine, and manageability. A biotin deficiency frequently results in heart issues, skin rashes, and hair loss because the vitamin is essential for the growth and formation of cells, fatty acids, and fats.
  • Hair care: Many people think that it can promote hair growth. Since Biotin cannot penetrate the skin, there hasn't been a single scientific study to support this particular function. As a result, topical application of Biotin is likely ineffective. Studies to date have mainly shown that it can make hair more workable and simple to comb. An oral supplement would be a much better option for treating hair loss than topical applications (although even the benefits to biotin supplements remain unclear). Various products containing biotin like biotin shampoo, hair grooming gel, and conditioner are available

Origin

Every living cell contains trace amounts of biotin, which is found naturally as the D-isomer. The majority of the combined forms of biotin found in animal and plant tissues are released during digestion by enzymatic hydrolysis. Organ meats, egg yolks, milk, fish, and nuts are food sources of biotin. dl-Biotin has been synthesized from 4-benzamido-3-ketotetrahydrothiophene and methyl y-formylbutyrate, and from 3,4-diamino-2-carbomethoxythiophene.

What does BIOTIN do in a formulation?

  • Hair conditioning
  • Moisturising
  • Skin conditioning
  • Smoothing

Safety profile

The safety of the cosmetic ingredient biotin, under consideration in the Cosmetics Ingredient Review (CIR) assessment, is determined using information obtained from the US Food and Drug Administration (FDA) and the cosmetics industry regarding the anticipated use of this ingredient in cosmetics. When used in accordance with good manufacturing practices, biotin is generally acknowledged as safe (GRAS) as a nutrient for human consumption, according to the U.S. FDA (GMP), [21CFR182.8159]. Biotin is not restricted from use in any way under the rules governing cosmetic products in the European Union (EU). The maximum leave-on-use concentration of biotin is 0.1% (in several formulation types). The CIR expert panel concludes that Biotin is safe as used in cosmetic formulations.

BIOTIN Alternatives

Technical profile

Property Values
Melting Point 232-233°C
Solubility Soluble in water and acetone
7

Commercial Selection : Grades containing solely BIOTIN

8
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