The Universal Selection Source: Cosmetics Ingredients

Patent

FUSION PROTEINS OF COLLAGEN-BINDING DOMAIN AND PARATHYROID HORMONE


Application Date:
Oct 8, 2015
USPTO Patent:
US 14743629
Abstract:

Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins ...

Inventors:
Robert C. Gensure, New York NY (US)
Joshua Sakon, Fayetteville AR (US)
Osamu Matsushita, Okayama (JP)
Tulasi Ponnapakkam, New York NY (US)
International Classification:
C12N 9/50 (20151008); A61Q 7/00 (20151008); A61K 38/29 (20151008); A61K 8/64 (20151008); A61K 38/48 (20151008); C07K 14/635 (20151008); A61K 8/66 (20151008)

Claims

What is claimed is:

1-60. (canceled)

Description

BACKGROUND

Osteoporosis is a bone disease characterized by thinning of bone tissue and loss of bone density over time. It is widely prevalent in the elderly. The National Osteoporosis Foundation estimates that by 2020 nearly 14 million Americans will suffer from osteoporosis. An additional 18 million may have low bone mass,...

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