TAGS: Sun Care
A pilot study conducted by the Center for Drug Evaluation and Research found out that several common sunscreen ingredients enter the bloodstream at levels high enough to trigger a government safety investigation. These ingredients continued to rise as daily use continued and then remained in the body for at least 24 hours after sunscreen use ended.
Further studies are now conducted to assess the systemic absorption and pharmacokinetics of the six active ingredients (avobenzone, oxybenzone, octocrylene, homosalate, octisalate, and octinoxate) in four sunscreen products under single- and maximal-use conditions.
Absorption of Sunscreen Actives in Plasma
All six sunscreen active ingredients were absorbed and found in plasma following application in either lotion or spray form. However, the presence of these ingredients in plasma does not suggest a safety issue and there were no serious drug-related adverse events reported in the trial, consistent with the excellent safety record associated with sunscreen active ingredients over decades of real-world use.
Personal Care Products Council and the Consumer Healthcare Products Association will continue to work cooperatively with FDA to determine what additional studies are needed to ensure the ongoing safety of sunscreen active ingredients in the marketplace.
Important Health Benefits of Sunscreens
The Personal Care Products Council (PCPC), the Consumer Healthcare Products Association (CHPA) and their member companies are aligned with FDA, the Centers for Disease Control and Prevention (CDC), the U.S. Surgeon General, the American Academy of Dermatology (AAD), the Skin Cancer Foundation and health professionals worldwide about the important health benefits sunscreens provide as part of a safe sun regimen to help prevent sunburn and reduce skin cancer risk.
FDA makes clear that the results of this study should not cause anyone to stop using sunscreen. Sunscreen is a crucial step in the fight against skin cancer and premature skin aging.
The associations will continue their work with FDA to ensure that consumers have access to products containing a broad variety of sunscreen active ingredients. The findings did not indicate that individuals should refrain from the use of sunscreen.
Source: Personal Care Products Council