OK
Cosmetics Ingredients
Industry News

BASF Collaborates to Develop 3D Bioprinted Skin Models for Bio-Actives’ Testing

Published on 2019-09-06. Edited By : SpecialChem

TAGS:  Skin Care    

BASF-CTIBiotech-3D-Model BASF Care Creations® and CTIBiotech announce the development of new 3D bioprinted human reconstructed skin model. The first tissue engineered skin model will allow researchers to study the development of anti-inflammatory properties of active ingredients. It will lead to the enhanced use of bio-actives for skin care applications.

The New Technology


  • BASF’s scientist’s 3D bioprinted skin model portfolio will be upgraded with 3D bioprinting technology of CTIBiotech.
  • The skin’s microenvironment is constantly monitored by macrophages for signals and help maintain skin homeostasis.
  • The new technology will help researchers to get an in-depth knowledge on the behavior of macrophages in skin.

Developing Innovative Ingredients for the Skin Care Market


Dr Sébastien Cadau, 3D tissue engineering specialist at BASF site in Lyon, France made a statement, “Compared to current in vitro methods, the 3D immune bioprinted skin developed with CTIBiotech will allow analysis more in line with human physiology and the immune role of macrophages. That’s how the technology is going to help us accelerate the development of innovative and highly reliable ingredients for the skin care market. Our understanding of an immunocompetent 3D skin provides the basis for developing and testing advanced cosmetic bio-actives for skincare applications.”

CTIBiotech and BASF have a long history of collaborations on innovative human skin models to advance human skin care,” said Prof Colin McGUCKIN, Chief Scientific Officer at CTIBiotech. “CTIBiotech hosts a team of world experts for human tissue engineering with 3D Bioprinting technology that will strengthen the success of this partnership also in the future.”

In early 2011, BASF and CTIBiotech became cooperation partners and by the year 2015 started working on the 3D tissue models. In 2018, they announced first results by demonstrating the production and regulation of sebum in a long-term culture of a 3D human sebaceous gland model.


Source: BASF
Back to Top