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The material selection platform
Cosmetics Ingredients
The material selection platform
Cosmetics Ingredients

CERAMIDE NP

CAS Number 100403-19-8
Chem/IUPAC Name: (9Z)-N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadec-9-enamide
EINECS/ELINCS No: 812-963-1
COSING REF No: 85476
CERAMIDE NP
Ceramide NP is one of several types of ceramides found naturally in skin. It plays a critical role as a major component of skin’s outer layers (healthy skin is generally composed of 50% ceramides, many of which are of the NP variety). “N” stands for the type of normal fatty acid correlated to this ingredient and “P” stands for its phytosphingosine base. Research shows skin care products containing ceramide NP can help improve the look and feel of dry or dehydrated skin thanks to its water retention properties. Ceramide NP has also been shown to reinforce skin’s barrier strength to better resist external stressors. Overall, it contributes to supple, resilient, hydrated skin. Its molecular formula is C36H71NO4.

What is CERAMIDE NP used for?

Ceramide NP is used in serums, creams, sunscreens, lotions, anti-aging products, night creams, oils.
  • Skin care: It helps improve the look and feel of dry or dehydrated skin thanks to its water retention properties. It also reinforces skin’s barrier strength, so it better resists external stressors and thus contributes to supple, resilient, hydrated skin overall

Origin

Ceramide NP is a lipid molecule included in a group of lipid molecules called ceramides. Ceramides are major lipid components in the stratum corneum of the human skin. It consists of a phytosphingosine backbone N-acylated with a saturated fatty acid (stearic acid).

What does CERAMIDE NP do in a formulation?

  • Hair conditioning
  • Moisturising
  • Skin conditioning

Safety profile

The Cosmetic Ingredient Review Expert Panel’s 2020 assessment concluded that ceramide ingredients are safe in cosmetics in the present practices of use. Their survey data looked at personal care products containing concentrations up to 0.00005-0.2% ceramide NP.

Technical profile

Property Values
Melting Point 98-110°C
Solubility Soluble in oil and few fatty alcohols
Insoluble in water
2
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